Neurologically, we see both increased numbers of dendritic spines and increased excitatory activities. Now a gene linking the two has been found. It is, of course, only one of many genes that can result in autism, but every advance in knowledge is good.
A connection between number of spines (meaning, number of connections) and increased excitatory activity shouldn’t be all that surprising. The more links you have in a social network, the more active you are likely to be. Too many friends, and your life can become overwhelmed. It works the same with neural networks.
It is my hope that a way can be found to reduce severe cases’ problems without reducing benefits too much.